Suppose you are a genetic counsellor, and a man and woman come to you with concerns that if they have a child together, it could have hemophilia. Also suppose that the man has an X-linked recessive form of hemophilia, but the woman does NOT, and that genetic tests reveal the woman is NOT a carrier for hemophilia. Which of the following is the best advice you could give them?

Question

Quizplus · Accepted Answer

Since the father has the X-linked recessive form of hemophilia and the mother does not carry the gene for hemophilia, all of their daughters will receive one X chromosome with the hemophilia gene from their father and one normal X chromosome from their mother, making them carriers. Their sons will receive the Y chromosome from their father and a normal X chromosome from their mother, so they will not have hemophilia.

Suppose You Are a Genetic Counsellor, and a Man and Woman