An X-linked recessive disease can skip generations because:

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Skipped generations are often observed in X-linked recessive disease pedigrees because the gene can be transmitted through female carriers.Males are hemizygous for genes on the X chromosome.Fathers cannot pass X-linked genes to their sons.X-linked recessive diseases are observed significantly more often in males than in females,because males need only one copy of the gene to express the disease.

An X-Linked Recessive Disease Can Skip Generations Because