Allison Has Severe Hay Fever

Allison has severe hay fever. What is the mechanism for her hypersensitivity?

A) IgE antibodies bound to mast cells bind an allergen. Histamine and other mediators are released, causing symptoms.
B) Allergens combine with antibodies, forming complexes that deposit in tissue and cause tissue damage.
C) T cells become activated after repeated exposure to an allergen. Chemical mediators are released about 24 hours later, resulting in inflammation of the skin.
D) Autoantibodies attack "self" cells and tissues, resulting in inflammation and tissue damage.