Which statement best describes heparin-induced thrombocytopenia (HIT)?
A) Immunoglobulin G immune-mediated adverse drug reaction that reduces circulating platelets
B) Hematologic reaction to heparin in which the bone marrow is unable to produce sufficient platelets to meet the body's needs
C) Immunoglobulin E-mediated allergic drug reaction that reduces circulating platelets
D) Cell-mediated drug reaction in which macrophages process the heparin and platelet complexes that are then destroyed by activated cytotoxic T cells.

Question

Quizplus · Accepted Answer

Heparin is a common cause of drug-induced thrombocytopenia.HIT is an immune-mediated,adverse drug reaction caused by immunoglobulin G antibodies that leads to increased platelet consumption and a decrease in platelet counts.None of the other options accurately describe HIT.

Which Statement Best Describes Heparin-Induced Thrombocytopenia (HIT)