A substance that could mediate the fever, shock, and tissue injury observed in patients with STSS is

Question

Quizplus · Accepted Answer

TNF-α (tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is one of the mediators of the acute phase reaction. It is capable of inducing fever, apoptotic cell death, cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulated production of TNF-α is implicated in a variety of human diseases including major depression, psoriasis, and cancer, as well as in the events leading to septic shock and tissue injury observed in infections such as Streptococcal Toxic Shock Syndrome (STSS).

A Substance That Could Mediate the Fever, Shock, and Tissue α\alphaα

A Substance That Could Mediate the Fever, Shock, and Tissue $\alpha$