Which of the sequences below best describes the sequential steps (numbered 1-5) in a signal transduction pathway that utilizes a G protein-coupled receptor?
1) The signal-receptor complex activates a G protein.
2) Protein kinases are activated.
3) A signal molecule binds to a receptor.
4) Target proteins are phosphorylated.
5) cAMP is produced.
A) 1, 2, 3, 4, 5
B) 3, 1, 2, 4, 5
C) 3, 1, 5, 2, 4
D) 1, 2, 5, 3, 4

Question

Quizplus · Accepted Answer

The correct sequence for a signal transduction pathway utilizing a G protein-coupled receptor is: 3) A signal molecule binds to a receptor, 1) The signal-receptor complex activates a G protein, 5) cAMP is produced (as a second messenger), 2) Protein kinases are activated (often as a result of the second messenger action), and 4) Target proteins are phosphorylated (as a result of kinase activity). This sequence accurately reflects the process from the initial signal reception to the final cellular response.

Which of the Sequences Below Best Describes the Sequential Steps