Misfolding of polypeptides is a serious problem in cells. Which of the following diseases are associated with an accumulation of misfolded polypeptides?
A) Alzheimer's only
B) Parkinson's only
C) Diabetes mellitus
D) Alzheimer's and Parkinson's

Question

Quizplus · Accepted Answer

Alzheimer's and Parkinson's diseases are both associated with the accumulation of misfolded polypeptides. In Alzheimer's, it's primarily the accumulation of beta-amyloid plaques and tau protein tangles, while in Parkinson's, it's the accumulation of alpha-synuclein.

Misfolding of Polypeptides Is a Serious Problem in Cells