If the DNA of a mammalian promoter region experiences increased methylation on cytosine (C) which of the following results is most likely to occur?
A) decreased chromatin condensation
B) activation of histone tails for enzymatic function
C) higher levels of transcription of certain genes
D) inactivation of the gene

Question

Quizplus · Accepted Answer

Increased methylation on cytosine within the promoter region of a gene typically leads to gene silencing or inactivation. This is because methylation can inhibit the binding of transcription factors necessary for the initiation of transcription, thereby reducing gene expression.

If the DNA of a Mammalian Promoter Region Experiences Increased