The most commonly occurring mutation in people with cystic fibrosis is a deletion of a single codon. What is the result of this type of mutation?
A) a base-pair substitution
B) a frameshift mutation
C) a polypeptide missing an amino acid
D) a polypeptide missing its N-terminus

Question

Quizplus · Accepted Answer

A deletion of a single codon in the DNA sequence results in the loss of a single amino acid in the polypeptide chain, but does not shift the reading frame of the mRNA.

The Most Commonly Occurring Mutation in People with Cystic Fibrosis