Hutchinson-Gilford progeria is an exceedingly rare human genetic disorder in which individuals look very old even as young children, experience very early senility and severe coronary artery disease, and have a life expectancy of 13 years. Which of the following statements represents the most likely assumption regarding this disorder?

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Quizplus · Accepted Answer

Hutchinson-Gilford progeria syndrome is caused by a mutation in the LMNA gene, which encodes for the lamin A protein. This mutation is not typically inherited but occurs as a new (de novo) mutation, explaining why it's rare and not often seen in multiple generations of the same family.

Hutchinson-Gilford Progeria Is an Exceedingly Rare Human Genetic Disorder in Which