Cells from advanced malignant tumors often have very abnormal chromosomes and an abnormal number of chromosomes. Which of the following best explains the association between malignant tumors and chromosomal abnormalities?
A) Cancer cells are no longer density-dependent.
B) Cancer cells are no longer anchorage-dependent.
C) Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities.
D) Transformation introduces new chromosomes into cells.

Question

Quizplus · Accepted Answer

Cancer cells often have mutations in genes that control cell cycle checkpoints, allowing cells with chromosomal abnormalities to continue dividing uncontrollably.

Cells from Advanced Malignant Tumors Often Have Very Abnormal Chromosomes