High levels of citric acid inhibit the enzyme phosphofructokinase, a key enzyme in glycolysis. Citric acid binds to the enzyme at a different location than the active site. This is an example of which of the following?
A) competitive inhibition
B) allosteric regulation
C) the specificity of enzymes for their substrates
D) positive feedback regulation

Question

Quizplus · Accepted Answer

Allosteric regulation occurs when a molecule binds to an enzyme at a site other than the active site, causing a change in the enzyme's activity. Since citric acid binds at a different location than the active site and affects the activity of phosphofructokinase, this is an example of allosteric regulation.

High Levels of Citric Acid Inhibit the Enzyme Phosphofructokinase, a Key