Sulfanilamide is an antimicrobial drug that mimics the shape of an important substrate for a particular bacterial enzyme, thereby inhibiting the enzyme. This type of inhibition is known as
A) allosteric inhibition.
B) competitive inhibition.
C) allosteric activation.
D) noncompetitive inhibition.
E) feedback inhibition.

Question

Quizplus · Accepted Answer

Sulfanilamide inhibits the bacterial enzyme by mimicking the shape of the important substrate, thereby competing with the substrate for the active site of the enzyme. This type of inhibition is known as competitive inhibition. Allosteric inhibition involves binding of a regulatory molecule at a site other than the active site, resulting in a conformational change that inhibits enzyme activity. Allosteric activation refers to binding of a molecule at a site other than the active site, resulting in a conformational change that increases enzyme activity. Noncompetitive inhibition involves binding of a molecule at a site other than the active site, leading to a conformational change that either inhibits or enhances enzyme activity. Feedback inhibition involves the product of a metabolic pathway inhibiting an enzyme earlier in the pathway.

Sulfanilamide Is an Antimicrobial Drug That Mimics the Shape of an Important