A polypeptide in a wild type microbe contains the sequence Leu-Pro-Tyr-Ser-Pro. A phenotypic variant of the species has the peptide sequence Leu-Pro-Cys-Ser-Pro. This is an example of a(n) ________ mutation.
A) nonsense
B) missense
C) silent
D) frameshift
E) inversion

Question

Quizplus · Accepted Answer

A missense mutation occurs when a single nucleotide change results in a different amino acid being incorporated into the polypeptide sequence. In this case, the substitution of the amino acid Tyr for Cys is a missense mutation.

A Polypeptide in a Wild Type Microbe Contains the Sequence