Small doses of antimicrobial drugs are effective in treatment of the late stages of Borrelia infection because the microbe is extremely susceptible.

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Borrelia burgdorferi, the bacterium that causes Lyme disease, is known to be resistant to many antimicrobial drugs. While early treatment with antibiotics is recommended, late-stage Lyme disease can be more difficult to treat and often requires longer courses of antibiotics at higher doses.

Small Doses of Antimicrobial Drugs Are Effective in Treatment of the Late