Why aren't positive inotropes such as the catecholamines used for long-term maintenance of cardiac muscle contraction dysfunctions?

Name: Why aren't positive inotropes such as the catecholamines used for long-term maintenance of cardiac muscle contraction dysfunctions?
Brand: Quizplus
Rating: 4.8 (54 reviews)

Question

Quizplus · Accepted Answer

Adrenergic receptor numbers decrease over time due to downregulation when exposed to high levels of catecholamines or other agonists for prolonged periods, leading to reduced effectiveness of these drugs for long-term use.

Why Aren't Positive Inotropes Such as the Catecholamines Used for Long-Term