If a drug is excreted via the liver, but after passing into the intestine is modified by gut bacteria to become more hydrophobic than it was originally, what can be said about the presence of this drug in the body?

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Quizplus · Accepted Answer

When a drug becomes more hydrophobic due to modification by gut bacteria, it is less likely to be reabsorbed in the intestines. However, in this case, the modification makes the drug more likely to be reabsorbed, thus increasing its presence in the body. This process, known as enterohepatic recirculation, can prolong the duration of a drug's presence in the body.

If a Drug Is Excreted Via the Liver, but After