Antibiotics such as kanamycin that function by reaching a relatively high serum level are considered ___________-dependent drugs, while those that need to be in the body continuously are considered ____________-dependent drugs.

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Antibiotics like kanamycin, which require a high serum level to be effective, are known as concentration-dependent drugs. This means their efficacy is related to the peak concentration they achieve in the blood relative to the pathogen's minimum inhibitory concentration (MIC). On the other hand, antibiotics that need to be present in the body for a prolonged period to be effective are called time-dependent drugs, indicating their effectiveness is more about the duration the drug concentration remains above the MIC rather than achieving a high peak concentration.

Antibiotics Such as Kanamycin That Function by Reaching a Relatively