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Why Does DNA Synthesis Only Proceed in the 5' to 3

Question 27

Multiple Choice

Why does DNA synthesis only proceed in the 5' to 3' direction?


A) Because DNA polymerases can only add nucleotides to the 3' end of a polynucleotide strand.
B) Because the 3' end of the polynucleotide molecule is more electronegative than the 5'end.
C) Because that is the direction in which the two strands of DNA unzip.
D) Because that is the only direction that the polymerase can be oriented.
E) Because the chromosomes are always aligned in the 5'to 3' direction in the nucleus.

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