A contemporary approach to pain management is to use on-line programs. Findings from studies are generally positive, but limited by:

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The statement mentions that the findings from studies using on-line pain management programs are generally positive, but limited by methodological issues. Therefore, option D is the best choice. Although options A, B, and C are potential limitations or challenges associated with on-line pain management, the statement does not suggest that they are the primary factors limiting the effectiveness of such programs.

A Contemporary Approach to Pain Management Is to Use On-Line