fMRI studies found that certain areas of the brain are activated when people with schizophrenia are processing harsh social feedback. One of the areas implicated is the:

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The rostral anterior cingulate has been found to be activated in fMRI studies of people with schizophrenia processing harsh social feedback. This area is involved in emotional regulation and processing errors, suggesting that individuals with schizophrenia may have difficulty regulating their response to negative feedback. The hippocampus is more commonly associated with memory and spatial navigation, while the left occipital area is involved in processing visual information and the right temporal pole is involved in social cognition and theory of mind.

FMRI Studies Found That Certain Areas of the Brain Are