With Regards to Ethics in Scientific Biomedical Research, Changes Have

With regards to ethics in scientific biomedical research, changes have been proposed for the Declaration of Helsinki, which were spurred by the following developments:

A) Increased research sponsored by for-profit organizations such as pharmaceutical companies
B) Increased non-profit agency and government scrutiny regarding the clinical populations being proposed for investigation
C) Less stringent guidelines on informed consent in order to increase the number of double-blind experimental designs
D) Decreased globalization of research which limits cross-culture generalizability