The plasma clearance of a substance can be used to calculate the glomerular filtration rate (GFR)if that substance is freely filtered at the glomerulus and which?
A) secreted and reabsorbed by the tubules.
B) neither reabsorbed nor secreted by the tubules.
C) secreted by the tubules.
D) reabsorbed by the tubules.

Question

Quizplus · Accepted Answer

If the substance is neither reabsorbed nor secreted by the tubules, then the plasma clearance of the substance will equal the GFR. This is because the only way for the substance to leave the body is through filtration at the glomerulus, and if it is not reabsorbed or secreted by the tubules, then its clearance will depend solely on the GFR. Examples of substances that meet these criteria include inulin and creatinine.

The Plasma Clearance of a Substance Can Be Used to Calculate