Because of countercurrent multiplication, the loop of Henle is able to establish a vertical osmotic gradient in the renal medulla ranging from 300 to 1,200 mosm/litre, despite the fact that the active salt pump of the ascending limb is able to produce only a 200 mosm/litre osmotic gradient at each horizontal level.

Question

Quizplus · Accepted Answer

Countercurrent multiplication allows the loop of Henle to establish a vertical osmotic gradient in the renal medulla that ranges from 300 to 1,200 mosm/litre, which is larger than the 200 mosm/litre gradient produced by the active salt pump of the ascending limb at each horizontal level.

Because of Countercurrent Multiplication, the Loop of Henle Is Able