As neurofibrillary tangles occur more frequently and affect multiple areas, the brain's ability to coordinate behavior and communicate with the body

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Neurofibrillary tangles are a hallmark of Alzheimer's disease and are associated with the deterioration of neurons in the brain. As they develop and spread, they can severely impair the brain's ability to coordinate behavior and communicate with the body, leading to significant cognitive and functional decline.

As Neurofibrillary Tangles Occur More Frequently and Affect Multiple Areas