Tay-Sachs disease, which produces severe motor and sensory disabilities, intellectual disability, and death at age 2 to 4 years, is found especially in

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Tay-Sachs disease is most commonly found in Ashkenazi Jews, with a carrier frequency of approximately 1 in 27 individuals. It is less common in other populations, including European Americans and Australian Americans.

Tay-Sachs Disease, Which Produces Severe Motor and Sensory Disabilities, Intellectual