When a single drug dose, such as a drink of alcohol or a snorted line of cocaine, leads to an uncontrollable binge, this situation is referred to as

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Priming refers to the phenomenon where exposure to a small amount of a drug triggers subsequent use of larger quantities, often leading to an uncontrollable binge. This can occur after just one drink or a small amount of a drug, as the initial use "primes" the brain for more intense reward and reinforcement. Drug cues and cravings may also play a role in triggering binge behavior, but priming specifically refers to the immediate escalation of drug use after an initial dose. The mesolimbic pathway is a brain circuit involved in reward and addiction, but it is not necessarily specific to binge behavior.

When a Single Drug Dose, Such as a Drink of Alcohol