Blessing (a male) and Thando (a female) are best friends. If their cross-gender friendship is typical of most, Blessing's biggest misperception concerning Thando would likely be

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Research has shown that men tend to over-perceive women's sexual interest in them in cross-gender friendships. This is known as the "sexual overperception bias." Therefore, Blessing is more likely to over-perceive Thando's level of sexual interest in him than any other misperception listed.

Blessing (A Male) and Thando (A Female) Are Best Friends