Oxyhemoglobin tends to give up oxygen where A) the pH is low. B) the tissues are warmer. C) the partial pressure of O₂ is low. D) the partial pressure of CO₂ is high. E) all of these occur.

Question

Quizplus · Accepted Answer

All of these factors can influence the affinity of hemoglobin for oxygen and its tendency to release oxygen to the surrounding tissues. 
- Low pH (acidic conditions) can promote the release of oxygen from hemoglobin, a phenomenon known as the Bohr effect. This is because acidic conditions reflect high metabolic activity and high demand for oxygen by the tissues. 
- Higher temperatures also promote oxygen release, likely because warmer tissues require more oxygen to sustain their metabolism. 
- When the partial pressure of oxygen is low (as in the peripheral tissues), hemoglobin tends to release oxygen to meet the oxygen demand of the tissues. 
- Conversely, when the partial pressure of carbon dioxide is high (as in metabolically active tissues), hemoglobin also tends to release oxygen to help buffer the acidity caused by CO2.

Therefore, all of these factors can contribute to the tendency of oxyhemoglobin to give up oxygen to the surrounding tissues.

Oxyhemoglobin Tends to Give Up Oxygen Where