Adding acetyl groups makes genes accessible to transcription by
A) increasing the pH of the cell.
B) making histones loosen their grip on the DNA molecule.
C) modifying the nucleotides of the promoter region of the DNA molecule.
D) enhancing the activity of RNA polymerase.
E) enhancing the development of a DNA-RNA hybrid.

Question

Quizplus · Accepted Answer

Acetyl groups added to histones mitigate the charge attraction between the histones and the negatively charged DNA molecule. Therefore, histones will loosen their grip on the DNA molecule, making the genes in the DNA molecule accessible to transcription.

Adding Acetyl Groups Makes Genes Accessible to Transcription by