The most serious Confederate threat to the Union blockade came from

Name: The most serious Confederate threat to the Union blockade came from
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The ironclad Virginia (also known as the Merrimack) posed a serious threat to the Union blockade as it was able to destroy two Union ships in March 1862 before being eventually defeated by the ironclad Monitor. While the other options may have contributed to the success of blockade runners, they did not pose as direct a threat as the Virginia.

The Most Serious Confederate Threat to the Union Blockade Came