During the Late Seventeenth and Early Eighteenth Centuries, How Did

During the late seventeenth and early eighteenth centuries, how did native Americans fare in Spain's American territories?

A) Mission life helped them to keep together and preserve their traditional work habits and language.
B) Their population declined as they suffered terrible epidemics.
C) Spanish colonial administrators enslaved Native Americans to work in silver mines.
D) Spanish soldiers slaughtered native Americans whenever they resisted the efforts of missionaries.
E) All of these choices