Protease inhibitors, which are effective anti-HIV drugs,

Question

Quizplus · Accepted Answer

Protease inhibitors prevent the synthesis of viral proteins by blocking the activity of the HIV protease enzyme. This prevents the processing of viral polyproteins into their functional components, which are essential for the assembly and release of new virus particles. Nucleoside analogs, on the other hand, interfere with viral DNA synthesis by mimicking the structure of nucleotides and incorporating into the growing DNA chain, while reverse transcriptase inhibitors prevent reverse transcription of viral RNA into DNA. mRNA synthesis inhibitors and tRNA activation prevent the expression of viral genes and protein synthesis, but these are not mechanisms targeted by protease inhibitors.

Protease Inhibitors, Which Are Effective Anti-HIV Drugs