A nurse reviews laboratory results for a client with glomerulonephritis.The client's glomerular filtration rate (GFR)is 40 mL/min as measured by a 24-hour creatinine clearance.How should the nurse interpret this finding? (Select all that apply.)

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The GFR refers to the initial amount of urine that the kidneys filter from the blood.In the healthy adult,the normal GFR ranges between 100 and 120 mL/min,most of which is reabsorbed in the kidney tubules.A GFR of 40 mL/min is drastically reduced,with the client experiencing fluid retention and risks for hypertension and pulmonary edema as a result of excess vascular fluid.

A Nurse Reviews Laboratory Results for a Client with Glomerulonephritis