Which of the following tripeptides is not hydrolysed by trypsin?

Question

Quizplus · Accepted Answer

Trypsin cleaves peptide bonds on the carboxyl side of basic amino acids (Arg and Lys), but not on the carboxyl side of acidic amino acids (Glu and Asp). In option C, the peptide bond between Glu and Ser cannot be hydrolyzed by trypsin because it is on the carboxyl side of Glu, which is an acidic amino acid. Therefore, option C is the correct answer. Option A has two arginine residues and one serine residue, all of which can be cleaved by trypsin. Option B has one arginine residue and one glutamic acid residue, both of which can be cleaved by trypsin. Option D has two arginine residues and one lysine residue, all of which can be cleaved by trypsin.

Which of the Following Tripeptides Is Not Hydrolysed by Trypsin