Choose the Best Description of Insulin Resistance from Among the Following

Choose the best description of insulin resistance from among the following.

A) The pancreas fails to produce insulin due to damage to alpha (α) cells.
B) The pancreas produces insulin but fails to secrete a sufficient amount when blood glucose is high.
C) The pancreas secretes insulin, but the insulin does not work as effectively on the tissue receptors.
D) The pancreas secretes glucagon instead of insulin in response to high blood glucose.