In sensitized persons, immediate hypersensitivity responses are primarily the result of liberation of vasoactive substances by the action of which of the following?
A) Activated T lymphocytes on smooth muscle cells
B) Immunoglobulin A on basophils and mast cells
C) Immunoglobulin A on neutrophils and eosinophils
D) Immunoglobulin E on basophils and mast cells
E) Immunoglobulin E on neutrophils and eosinophils
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