Adhesion of white blood cells to the endothelium is:

Question

Quizplus · Accepted Answer

Adhesion of white blood cells to the endothelium is dependent on activation of integrins, which allows them to bind to molecules on the surface of the endothelial cells. Selectins actually help facilitate this adhesion process by slowing down the white blood cells and bringing them in closer contact with the endothelium. Histamine release may increase adhesion by inducing the expression of adhesion molecules, but inhibiting histamine release would not decrease adhesion. The adhesion of white blood cells is actually greater on the venous side of the circulation due to lower blood flow and shear stress.

Adhesion of White Blood Cells to the Endothelium Is