A 29-year-old man has a serum potassium of 2.1 mEq/L (normal: 3.5 to 5.0 mEq/L) and a serum sodium of 125 mEq/L (normal: 135 to 147 mEq/L). Which of the following sets of changes best describe the resting membrane potential and K⁺ Nernst potential in a typical neuron in this man compared with normal? (Assume normal intracellular ion concentrations.) $$\begin{array} { l l l } & \underline{\mathrm { K } ^ { + } \text {Nernst Potential } }& \underline{\text { Resting Membrane Potential }} \ \text { A. } & \text { Less negative } & \text { Less negative } \ \text { B. } & \text { Less negative } & \text { No change } \ \text { C. } & \text { Less negative } & \text { More negative } \ \text { D. } & \text { More negative } & \text { Less negative } \ \text { E. } & \text { More negative } & \text { More negative } \ \text { F. } & \text { More negative } & \text { No change } \ \text { G. } & \text { Nochange } & \text { Less negative } \end{array}$$

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The Answer of A 29-year-old man has a serum potassium of 2.1 mEq/L (normal: 3.5 to 5.0 mEq/L) and a serum sodium of 125 mEq/L (normal: 135 to 147 mEq/L). Which of the following sets of changes best describe the resting membrane potential and K⁺ Nernst potential in a typical neuron in this man compared with normal? (Assume normal intracellular ion concentrations.) $$\begin{array} { l l l } & \underline{\mathrm { K } ^ { + } \text {Nernst Potential } }& \underline{\text { Resting Membrane Potential }} \ \text { A. } & \text { Less negative } & \text { Less negative } \ \text { B. } & \text { Less negative } & \text { No change } \ \text { C. } & \text { Less negative } & \text { More negative } \ \text { D. } & \text { More negative } & \text { Less negative } \ \text { E. } & \text { More negative } & \text { More negative } \ \text { F. } & \text { More negative } & \text { No change } \ \text { G. } & \text { Nochange } & \text { Less negative } \end{array}$$

A 29-Year-Old Man Has a Serum Potassium of 2