Which of the following is the mechanism of action of cyclosporine?
A) It blocks the complement cascade.
B) It blocks the activity of activated Th1 T cells.
C) It directly blocks CTL activity.
D) It interferes with activation of Th2 T cells.
E) It is an anti-inflammatory interfering with leukotriene function.

Question

Quizplus · Accepted Answer

Cyclosporine blocks the activity of activated Th1 T cells by inhibiting the production of interleukin-2 (IL-2), a cytokine that is necessary for the activation and proliferation of T cells. This results in suppression of the immune response, which is useful in preventing transplant rejection and treating autoimmune diseases.

Which of the Following Is the Mechanism of Action of Cyclosporine