The pathogenicity of primary tuberculosis is due to the fact that the mycobacteria
A) are not phagocytized.
B) prevent fusion of lysosomes with vesicles.
C) form a pseudomembrane.
D) destroy helper T cells.
E) are carried by macrophages to a variety of sites.

Question

Quizplus · Accepted Answer

Mycobacteria that cause tuberculosis are able to prevent fusion of lysosomes with vesicles, which allows them to survive and replicate within phagocytic cells. This leads to the formation of granulomas and tissue damage, resulting in the pathogenicity of the disease.

The Pathogenicity of Primary Tuberculosis Is Due to the Fact