Once infected with Trypanosoma brucei,the patient's immune system cannot clear the infection and develop immunity because the parasite

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Trypanosoma brucei changes its glycoprotein surface antigens every time it replicates, which allows it to evade the immune system and continue to cause infection. This mechanism is known as antigenic variation and makes it difficult for the immune system to recognize and develop immunity against the parasite.

Once Infected with Trypanosoma Brucei,the Patient's Immune System Cannot Clear