In an enzymatic reaction involving NADH or NADPH, reduction of a substrate accompanies the oxidation of these carrier molecules to NAD⁺ or NADP⁺, respectively. What else typically happens in such a reaction?

Question

Quizplus · Accepted Answer

In a reduction reaction, NADPH (or NADH) is oxidized, donating a hydride ion to the substrate. A substrate can also capture a proton from the surroundings, creating two C-H bonds. The carrier is converted to its oxidized form (NADP⁺ or NAD⁺).

In an Enzymatic Reaction Involving NADH or NADPH, Reduction of a Substrate