Upon Heavy Damage to the Cell's DNA, the Normal Replicative

Upon heavy damage to the cell's DNA, the normal replicative DNA polymerases may stall when encountering damaged DNA, triggering the use of backup translesion polymerases. These backup polymerases …

A) lack 3′-to-5′ exonucleolytic proofreading activity.
B) are replaced by the replicative polymerases after adding only a few nucleotides.
C) can create mutations even on undamaged DNA.
D) may recognize specific DNA damage and add the appropriate nucleotide to restore the original sequence.
E) All of the above.