Indicate true (T) and false (F) statements below regarding the initiation of replication in human cells. Your answer would be a four-letter string composed of letters T and F only, e.g. TFFF.
( ) Tens of thousands of replication origins are used each time a cell in our body replicates its DNA.
( ) Different cells in our body use different sets of replication origins.
( ) Both replication forks in a replication bubble are normally active in replication.
( ) Gene expression and chromatin structure can affect the choice of the origins to use as well as the order in which they are activated.

Question

Indicate true (T) and false (F) statements below regarding the initiation of replication in human cells. Your answer would be a four-letter string composed of letters T and F only, e.g. TFFF.
( )	Tens of thousands of replication origins are used each time a cell in our body replicates its DNA.
( )	Different cells in our body use different sets of replication origins.
( )	Both replication forks in a replication bubble are normally active in replication.
( )	Gene expression and chromatin structure can affect the choice of the origins to use as well as the order in which they are activated.

Quizplus · Accepted Answer

Human cells have probably hundreds of thousands of potential origins, out of which about 40,000 are used each time a cell divides. Depending on gene expression and chromatin state, different sets of origins can be used in different cells of the body. Once an origin is activated, the resulting replication bubble expands on both sides of the origin.

Indicate True (T) and False (F) Statements Below Regarding the Initiation