Sort the following events in the order that they occur during transcription initiation in Escherichia coli. Your answer would be a four-letter string composed of letters A to D only; e.g. DCAB.
(A) Abortive initiation trials
(B) ? Factor release from the RNA polymerase holoenzyme
(C) Binding of the holoenzyme to the promoter in the "closed" complex
(D) Formation of the transcription bubble

Question

Sort the following events in the order that they occur during transcription initiation in Escherichia coli. Your answer would be a four-letter string composed of letters A to D only; e.g. DCAB.
(A)	Abortive initiation trials
(B)	? Factor release from the RNA polymerase holoenzyme
(C)	Binding of the holoenzyme to the promoter in the "closed" complex
(D)	Formation of the transcription bubble

Quizplus · Accepted Answer

In bacterial transcription initiation, binding of the RNA polymerase holoenzyme to the promoter region in the closed complex is followed by the formation of the open complex involving the formation of the transcription bubble. After a number of abortive initiations, RNA polymerase clears the promoter and ? factor is released.

Sort the Following Events in the Order That They Occur