Transcription regulation has similarities and differences in bacteria and in eukaryotes. Which of the following is correct in this regard?
A) Most bacterial genes are regulated individually, whereas most eukaryotic genes are regulated in clusters.
B) The rate of transcription for a eukaryotic gene can vary in a much wider range than for a bacterial gene (which is, at most, only about 1000-fold).
C) DNA looping for gene regulation is the rule in bacteria but the exception in eukaryotes.
D) Transcription regulators in both bacteria and eukaryotes usually bind directly to RNA polymerase.
E) The default state of both bacterial and eukaryotic genomes is transcriptionally active.

Question

Quizplus · Accepted Answer

Variation in transcription rates across the genome is much greater in eukaryotic cells (about one million-fold) compared to prokaryotic cells (about one thousand-fold). In eukaryotes, genes are often transcribed and regulated individually, and DNA looping occurs in the regulation of nearly every gene. In these cells, transcription regulators often assemble in groups and do not directly contact RNA polymerases. The default state of most eukaryotic DNA packaged into nucleosomes is off.

Transcription Regulation Has Similarities and Differences in Bacteria and in Eukaryotes