The time courses of seeded actin polymerization under two different conditions are compared in the following graph. If the overall kₒn for polymerization is known to be the same under both of these conditions, which curve-(1) or (2)-corresponds to the condition with a higher kₒff rate constant? Which one corresponds to a higher Cc for polymerization?
A) Curve (1); curve (1)
B) Curve (1); curve (2)
C) Curve (2); curve (1)
D) Curve (2); curve (2)
E) Curve (2); both curves have the same Cc.

Question

The time courses of seeded actin polymerization under two different conditions are compared in the following graph. If the overall kₒn for polymerization is known to be the same under both of these conditions, which curve-(1) or (2)-corresponds to the condition with a higher kₒff rate constant? Which one corresponds to a higher Cc for polymerization? 
A) Curve (1); curve (1) 
B) Curve (1); curve (2) 
C) Curve (2); curve (1) 
D) Curve (2); curve (2) 
E) Curve (2); both curves have the same Cc.

Quizplus · Accepted Answer

The condition corresponding to curve (2) has a higher kₒff and hence a higher Cc, manifested as a lower steady-state percentage of incorporated subunits, as well as an overall lower net polymerization rate before reaching the steady state.

The Time Courses of Seeded Actin Polymerization Under Two Different