In the following schematic drawing of a polarized neutrophil engaged in chemotaxis, in what region (a or b) does Rac activity dominate? What other member of the Rho family dominates at the other region?
A) Region (a); Rho
B) Region (a); Cdc42
C) Region (b); Rho
D) Region (b); Cdc42

Question

In the following schematic drawing of a polarized neutrophil engaged in chemotaxis, in what region (a or b) does Rac activity dominate? What other member of the Rho family dominates at the other region? 
A) Region (a); Rho 
B) Region (a); Cdc42 
C) Region (b); Rho 
D) Region (b); Cdc42

Quizplus · Accepted Answer

At the front of the cell (toward the source of the bacterial peptides), the Rac pathway dominates and limits the activity of the Rho GTPase to the other end of the cell.

In the Following Schematic Drawing of a Polarized Neutrophil Engaged