Indicate true (T) and false (F) statements below regarding mitosis and the changes that it brings about compared to interphase. Your answer would be a four-letter string composed of letters T and F only, e.g. TFTF.
( ) Microtubules become greatly stabilized in mitosis compared to interphase.
( ) The number of ?-tubulin ring complexes in the centrosomes increases greatly during mitosis compared to interphase.
( ) Chromosomes stabilize mitotic microtubules through activation of Ran monomeric G protein.
( ) A bipolar spindle can be formed even in the absence of centrosomes.

Question

Indicate true (T) and false (F) statements below regarding mitosis and the changes that it brings about compared to interphase. Your answer would be a four-letter string composed of letters T and F only, e.g. TFTF.
( )	Microtubules become greatly stabilized in mitosis compared to interphase.
( )	The number of ?-tubulin ring complexes in the centrosomes increases greatly during mitosis compared to interphase.
( )	Chromosomes stabilize mitotic microtubules through activation of Ran monomeric G protein.
( )	A bipolar spindle can be formed even in the absence of centrosomes.

Quizplus · Accepted Answer

Mitosis is accompanied by a dramatic reorganization of the microtubule cytoskeleton, with a significant increase in microtubule instability. At the same time, centrosome maturation greatly increases microtubule nucleation. The capture of microtubules by chromosomes stabilizes microtubules in part by activating Ran, a monomeric GTPase. The ability of mitotic chromosomes to stabilize and organize microtubules makes it possible to form bipolar spindles even in the absence of centrosomes.

Indicate True (T) and False (F) Statements Below Regarding Mitosis